Distribution: Widely distributed on both sides of the Cascades crest in Washington; Alaska to California, east across North America to the Atlantic Coast.
Habitat: In deep, rich soil or near moisture, sagebrush deserts, shady lowlands and mountain slopes, sea level to subalpine.
Conservation Status: Not of concern
Rhizomatous perennials 1-3 meters tall.
Simple, opposite, petiolate with stipules at base; margins serrate to dentate; stinging and nonstinging hairs present on both surfaces, or stinging hairs on lower surface only.
Plants monoecious or dioecious. Sepals 4, petals absent, stamens 4 and opposite the sepals, ovary superior.
Achene enclosed within the dry sepals.